COST Action CA15106: C-H Activation in Organic Synthesis (CHAOS)

Mission Statement

The main aim of this action is to render C-H activation a truly versatile, practical and general tool for organic chemistry, applicable in both industry & academia.
In principal, organic chemists have the tools in hand to prepare any thermodynamically stable molecule by one way or the other. However, even though great achievements have been made in the past century, most of the bond forming reactions rely on preactivated substrates. Additionally, in complex synthesis, protecting group techniques are often required either to block alternative sites of reactivity, or to protect functional groups labile under reaction conditions required for a specific step of a sequence. The paradigm in organic synthesis has shifted from “getting the job done (the molecule synthesized)” towards getting the job done in the most efficient way possible. The method of metal catalysed C-H activation of organic small molecules has great potential in this regard. At the moment, the field has included many examples of transformations which can be carried out only on specific types of substrates and only few contributions deal with the application of C-H activation in the synthesis of complex molecules such as natural products. Additionally, applications of C-H activation in industrial processes are scarce. Hence, broad applicability, similar to the well establish cross-coupling reactions, has to be established. The time is ripe now to make a big collaborative effort in the area of C-H activation.


Michael Schnürch

Michael Schnürch


MS has carried out his diploma and PhD thesis in the group of Prof. Peter Stanetty and received his PhD in 2005 from Vienna University of Technology (VUT). During his PhD-studies, he was on a 4 month sabbatical in Canada where he worked in the group of Prof. Victor Snieckus at Queens University (Kingston, Ontario). He was then Post-Doc with Prof. Dalibor Sames at the Columbia University in New York City (as Erwin Schrödinger fellow) and conducted research in the field of sp3 C-H activation.

Dr Gerard McGlacken

Dr Gerard McGlacken


Dr Gerard McGlacken obtained his Ph.D. at the National University of Ireland, Galway. He then moved to the University of York (UK) where he worked on organometallic transformations with Prof. Ian J. S. Fairlamb. A year later, he took up a ‘Molecular Design and Synthesis Post-Doctoral Fellowship’ at Florida State University (US) working with Prof. Robert A. Holton. He obtained a Lectureship position at University College Cork, Ireland in 2007.

Core Group

Core Group


Chair of the Action and member of Core Group. Michael is also the member of WG1.

Tatiana BESSET

Tatiana BESSET is the member of Core Group. She is the manager of Short Term Scientific Meetings (STSM) within the cost action. She is also the member of WG2.


Zoltan NOVAK



Cristina NEVADO



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