The objective of WG 1 is to develop novel processes for the construction of C‐C bond(s) via transition metal catalyzed C‐H activation for the versatile functionalization and construction of aromatic and heterocyclic systems.
The objective of WG2 is to make important advances in this key area, as represented – but not limited to – the following:
The discovery of diverse C-X bond forming methods accessed via catalytic C-H activation.
The discovery of new principles behind this reactivity, based on a combination of catalyst development and mechanistic insights working hand-in-hand.
Application of the new discoveries to the synthesis of important molecules.
The objective of the “Asymmetric C-H activation” Working Group is to design, investigate and develop new strategies to construct high value-added enantiopure building blocks by direct functionalization of unactivated C-H bonds of non-prefunctionalized substrates. Our ambition is to discover both:
– new asymmetric transformations occurring via C-H activation
– powerful, general and easily accessible chiral catalysts prompt to catalyze such transformations.
The objective of the “Mechanistic investigations in C-H activation” Working Group is the interrogation of reaction mechanisms underpinning C-H activation chemistry. This working group aims to be integrated in and contribute towards the goals set out for the other three working groups of the CHAOS Action.